The actor has played Dr. Alex Karev since the 2005 pilot. It started with a letter and ended with a bombshell. Justin Chambers, who plays Dr. Alex Karev in the long-running ABC medical drama "Grey's ...

"Wasn't he with someone?" Katherine Heigl may not be on "Grey's Anatomy" anymore, but that didn't stop her from offering up her opinion on the show's shocking twist involving Alex and Izzie last ...

"Grey's Anatomy" has confirmed that next week's episode will finally explain Alex Karev's off-screen exit. The popular medical drama released a new trailer promoting Alex's goodbye episode, featuring ...

When "Grey's Anatomy" premiered as a mid-season replacement in the spring of 2005 on ABC, fans were introduced to the medical drama's five original surgical interns: Meredith Grey (Ellen Pompeo), Alex ...