A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...

Even though amide bonds are everywhere—they hold proteins together and are essential components in many drugs—forging this molecular motif in a reaction flask can be challenging. For example, making ...

In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity. Certain medicines make use of reactions ...

It’s dinnertime, and the only food in your house is a can of beans and a box of spaghetti. What can you make? A new mapping method that combines known reactants in unfamiliar ways can help organic ...

In order to fully understand the underlying factors that govern the outcome of a chemical reaction, chemists need the ability to monitor and follow the reaction. NMR spectroscopy is an excellent way ...