Interleukin-6 (IL-6) is a multifaceted cytokine that serves as a critical mediator in immune regulation, inflammation and tissue regeneration. Its activity is mediated through several signalling ...

Researchers have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6). Researchers at The University of Texas ...

CI denotes confidence interval, and SNP single-nucleotide polymorphism. Sequencing reads were aligned to the hg19 reference genome. A SIFT (sorting intolerant from tolerant) score of less than 0.05 ...

However, imbalances of IL-6 — too much or too little — can cause disease, even in the absence of infection. Excess IL-6 is central to the pathogenesis of inflammatory reactions like rheumatoid disease ...

Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine ...

Interleukin-6 (IL-6) is a pleiotropic cytokine that may play a role in the regulation of various aspects of the immune response, inflammation, hematopoiesis, and bone metabolism. IL-6 acts by binding ...

In a recent study posted to Research Square*, researchers reported that plasma interleukin (IL)-6 levels in patients with acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 ...

Possible association of postmeiotic segregation increased 2 (PMS 2) gene deletion and myelodysplastic syndrome. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does ...

As baseline levels of IL-6 prior to hemodialysis AVF creation increase, so does the risk for AVF failure. Elevated levels of interleukin-6 (IL-6) prior to surgery to create an arteriovenous fistula ...

The inflammatory bowel diseases (IBDs) are chronic intestinal disorders that are typically categorized as one of two subtypes: Crohn’s disease and ulcerative colitis. 1 Ulcerative colitis is limited ...