Hematopoietic stem cell transplantation (HCT) is a treatment for some life-threatening cancers and nonmalignant disorders. As ...

Researchers used CRISPR to remove the CD33 protein from donor stem cells, protecting healthy blood cells from therapies that target leukemia. In a 30-patient trial, the edited cells rebuilt blood ...

Children who survive a stem-cell transplant only to watch their own donor cells attack their organs now have a first-of-its-kind treatment option. The FDA approved Ryoncil, an allogeneic ...

Among patients with primary CNS lymphoma who respond to induction therapy, high-dose chemotherapy with stem cell transplant ...

Experts at City of Hope, one of the nation's largest and most advanced cancer research and treatment organizations, are ...

Two more people appear to be free of HIV after stem cell transplants for cancer treatment, according to case presentations ...

Stem cell transplants remain essential for blood cancers, with expanded donor options including half-matched family members and umbilical cord blood. Cyclophosphamide has improved graft-versus-host ...

CAR T cell therapy and stem cell transplant are among the most advanced treatment options for blood cancers such as leukemia, ...

Growth impairment is a common late effect of childhood stem cell transplantation. A Japan-wide study found that growth ...

December 20, 2010 — Replacing host stem cells with donor-derived cells homozygous for the CCR5 gene variant Δ32 (CCR5Δ32/Δ32) resulted in the HIV viral reservoir being reduced over time, strongly ...

As spirometry requires coordinated deep breathing and can be challenging for children to perform, researchers from the USA, as part of the TRANSPIRE study investigating lung complications in children ...